Application of a Gradient Retention Model Developed by Using Isocratic Data for the Prediction of Retention, Resolution, and Peak Asymmetry in Ion Chromatography

Autor:	Melita Luša, Štefica Cerjan-Stefanović, Marko Rogošić, Tomislav Bolanča, Šime Ukić
Rok vydání:	2009
Předmět:	gradient elution ion chromatography peak asymmetry resolution retention model Work (thermodynamics) Chromatography Resolution (mass spectrometry) Chemistry Elution media_common.quotation_subject Clinical Biochemistry Ion chromatography Pharmaceutical Science Experimental data Biochemistry Method development Asymmetry Analytical Chemistry Gradient elution media_common
Zdroj:	Journal of Liquid Chromatography & Related Technologies. 32:1373-1391
ISSN:	1520-572X 1082-6076
DOI:	10.1080/10826070902900228
Popis:	In this work a model was developed for the prediction of retention time, resolution, and peak asymmetry in gradient elution mode by using isocratic experimental data. The predictive performance and generalization ability of the developed model was extensively tested by using an external experimental data set. The analysis of errors was performed in order to discuss and explain characteristics of the model. It was shown that the model performed satisfactorily and that it could be used for a modeling procedure in the optimization part of the ion chromatography method development.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9580d6524f7e8416211f54efa884a4ea https://doi.org/10.1080/10826070902900228 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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