Plasma glucocorticoid elevation and desynchronization of the estrous cycle following unpredictable stress in the rat
| Autor: | J.R. Bassett, Barbara M. White, K.D. Cairncross, Irina Pollard |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
endocrine system
medicine.medical_specialty medicine.medical_treatment Period (gene) Biology medicine.disease_cause chemistry.chemical_compound Estrus Corticosterone Pregnancy Internal medicine medicine Psychological stress Animals Humans reproductive and urinary physiology Electric stimulation General Environmental Science Estrous cycle urogenital system Electric Stimulation Rats Steroid hormone Endocrinology chemistry General Earth and Planetary Sciences Plasma corticosterone Female hormones hormone substitutes and hormone antagonists Glucocorticoid Stress Psychological medicine.drug |
| Zdroj: | Behavioral biology. 14(01) |
| ISSN: | 0091-6773 |
| Popis: | Exposure of female Wistar rats to a signalled unpredictable 5-day stress regimen induced extreme plasma corticosterone elevation at all four stages of the estrous cycle. The corticosterone level at proestrus was significantly higher than at the other three stages of the cycle in both control and stressed groups. This rise in plasma corticosterone became evident only in late proestrus. It was observed that the estrous cycles of 50% of the rats became desynchronized over the 5-day stress period; a steroid hormone imbalance is suggested as a possible factor contributing to this desynchrony. |
| Databáze: | OpenAIRE |
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