Does umbilical cord blood-derived CD34+ cell concentration depend on the weight and sex of a full-term infant?
| Autor: | Sheeba Afreen, Tulika Chandra, Ashutosh Kumar, Uma Singh, Ashish Gupta |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Cord Birth weight Antigens CD34 Gestational Age Umbilical cord Andrology Sex Factors Pregnancy medicine Birth Weight Humans business.industry Umbilical Cord Length Infant Newborn Gestational age Hematology medicine.disease Fetal Blood Hematopoietic Stem Cells Low birth weight medicine.anatomical_structure Oncology Cord blood Pediatrics Perinatology and Child Health Blood Banks Female medicine.symptom business |
| Zdroj: | Journal of pediatric hematology/oncology. 34(3) |
| ISSN: | 1536-3678 |
| Popis: | Umbilical cord blood has recently been considered as an alternative source of hematopoietic progenitor cells for clinical application. Patient survival in allogenic cord blood transplantation is critically dependent on the cord blood-derived total nucleated cell count and the total CD34 cell count/kg of the body weight. A number of factors such as maternal age, gestational age, newborn's sex and weight, umbilical cord length, and placental weight can influence the volume, amount of mononuclear cells, and the CD34 cell concentration. Cord blood was collected from normal vaginal and cesarean deliveries. It was immediately processed and assessed for the total nucleated cell count and CD34 cell concentration. Assessment of maternal and neonatal parameters such as gestational age, baby's birth weight, and sex was carried out with the CD34 cell concentration. The mean CD34 cell concentration was 0.21±0.24% for the group with |
| Databáze: | OpenAIRE |
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