Successful treatment for perinephric abscess with recombinant human granulocyte colony-stimulating factor following nephrectomy in a patient of myelodysplastic syndrome: a case report
| Autor: | Kiyokazu Toyoda, Nobuyuki Hirakawa, Masaru Minoda, Masanori Takeuchi, Kazuo Tamura |
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| Rok vydání: | 1990 |
| Předmět: |
Adult
Male medicine.medical_specialty Neutropenia medicine.drug_class medicine.medical_treatment Antibiotics Granulocyte Nephrectomy Adipose capsule of kidney hemic and lymphatic diseases Internal medicine Granulocyte Colony-Stimulating Factor medicine Humans Pharmacology Hematology business.industry Granulation tissue Abscess Recombinant Proteins Surgery Granulocyte colony-stimulating factor Renal Abscess medicine.anatomical_structure Myelodysplastic Syndromes Drug Evaluation Kidney Diseases business Granulocytes |
| Zdroj: | Biotherapy (Dordrecht, Netherlands). 2(3) |
| ISSN: | 0921-299X |
| Popis: | The 35-year-old man with myelodysplastic syndrome (MDS) and granulocytopenia with dry cough and high fever was eventually found to have a left perinephric abscess of Staphylococcus aureus. He underwent left nephrectomy and drainage of perinephric space in conjunction with appropriate antibiotics. However, because of persistent granulocytopenia, Staph. aureus never cleared up with formation of only poor granulation. Recombinant human granulocyte colony-stimulating factor (G-CSF) was added to the above treatment leading to prompt improvement in granulocytopenia and emergence of the good granulation tissue. G-CSF will probably become one of the important agents in treating MDS with granulocytopenia. |
| Databáze: | OpenAIRE |
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