Design, synthesis, in vitro, and in silico enzymatic evaluations of thieno[2,3-b]quinoline-hydrazones as novel inhibitors for α-glucosidase

Autor:	Milad Noori, Mryam Rastak, Mohammad Halimi, Minoo Khalili Ghomi, Mrjan Mollazadeh, Maryam Mohammadi-Khanaposhtani, Mohammad Hosein Sayahi, Zahra Rezaei, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Bagher Larijani, Mahmood Biglar, Massoud Amanlou, Mohammad Mahdavi
Rok vydání:	2022
Předmět:	Molecular Docking Simulation Structure-Activity Relationship Molecular Structure Organic Chemistry Drug Discovery Hydrazones Quinolines Glycoside Hydrolase Inhibitors alpha-Glucosidases Acarbose Saccharomyces cerevisiae Molecular Biology Biochemistry
Zdroj:	Bioorganic Chemistry. 127:105996
ISSN:	0045-2068
Popis:	In the development of novel anti-α-glucosidase agents, we synthesized novel thieno[2,3-b]quinoline-hydrazones 9a-n by facile and efficient conventional chemical reactions. These compounds were characterized by IR
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957553a90bed9993a8ed89c2d3201a1c https://doi.org/10.1016/j.bioorg.2022.105996 Zobrazit plný text záznamu Full Text from ScienceDirect