Structure and function of the ventricular tachycardia isthmus
Autor: | Nicholas S. Peters, Elaine Wan, Andrew L. Wit, Hirad Yarmohammadi, Edward J. Ciaccio, Elad Anter, James Coromilas, Hasan Garan |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Substrate mapping medicine.medical_treatment Myocardial Infarction Catheter ablation Reentrant circuit Ventricular tachycardia 0903 Biomedical Engineering Heart Conduction System Physiology (medical) Internal medicine Medicine Animals Humans In patient 1102 Cardiorespiratory Medicine and Haematology Human studies business.industry medicine.disease Vt ablation Ablation Isthmus Structure and function Disease Models Animal Mapping Cardiovascular System & Hematology Cardiology cardiovascular system Catheter Ablation Tachycardia Ventricular Cardiology and Cardiovascular Medicine business Electrophysiologic Techniques Cardiac |
Zdroj: | Heart rhythm. 19(1) |
ISSN: | 1556-3871 |
Popis: | Catheter ablation of postinfarction reentrant ventricular tachycardia (VT) has received renewed interest owing to the increased availability of high-resolution electroanatomic mapping systems that can describe the VT circuits in greater detail, and the emergence and need to target noninvasive external beam radioablation. These recent advancements provide optimism for improving the clinical outcome of VT ablation in patients with postinfarction and potentially other scar-related VTs. The combination of analyses gleaned from studies in swine and canine models of postinfarction reentrant VT, and in human studies, suggests the existence of common electroanatomic properties for reentrant VT circuits. Characterizing these properties may be useful for increasing the specificity of substrate mapping techniques and for noninvasive identification to guide ablation. Herein, we describe properties of reentrant VT circuits that may assist in elucidating the mechanisms of onset and maintenance, as well as a means to localize and delineate optimal catheter ablation targets. |
Databáze: | OpenAIRE |
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