FADE PROFILES DURING SPONTANEOUS OFFSET OF NEUROMUSCULAR BLOCKADE: VECURONIUM AND GALLAMINE COMPARED
| Autor: | A.C. Pearce, R.M. Jones, S.J. Power |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Adult
Male Time Factors Offset (computer science) Neuromuscular transmission Humans Medicine Ulnar Nerve Aged Neuromuscular Blockade Vecuronium Bromide Gallamine Triethiodide business.industry Gallamine triethiodide Middle Aged Neuromuscular Blocking Agents Blockade Anesthesiology and Pain Medicine Anesthesia Female Cholinesterase Inhibitors Neuromuscular blockade monitoring Fade business Muscle Contraction medicine.drug |
| Zdroj: | British Journal of Anaesthesia. 60:486-490 |
| ISSN: | 0007-0912 |
| DOI: | 10.1093/bja/60.5.486 |
| Popis: | The characteristics of the train-of-four (TOF) response have been studied electromyographically during the onset and the spontaneous offset of neuromuscular blockade induced with vecuronium or gallamine. During the onset of blockade, at 75% depression of initial twitch height, gallamine was associated with significantly more TOF fade than vecuronium. Both agents were associated with significantly less fade during onset than during spontaneous offset. When the two neuromuscular blocking drugs were compared during spontaneous offset they showed a similar degree of fade during early offset (up to 50% recovery of initial twitch height). However, during late spontaneous offset, when the initial twitch height had recovered to 75% of control values, vecuronium was associated with more fade than gallamine. |
| Databáze: | OpenAIRE |
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