Hypohidrosis induced by topiramate in an adult patient
Autor: | Styliani Karachristianou, Evangelos Papamichalis, Panagiota Boura, George Georgiadis, Alexandros Sarantopoulos |
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Rok vydání: | 2013 |
Předmět: |
Adult
Male Hyperthermia Topiramate medicine.medical_specialty Neurology Fever Side effect Physical exercise Fructose SWEAT Epilepsy Complex Partial Environmental temperature medicine Humans Adverse effect Hypohidrosis business.industry General Medicine medicine.disease Dermatology Anesthesia Anticonvulsants Neurology (clinical) business medicine.drug |
Zdroj: | Epileptic Disorders. 15:203-206 |
ISSN: | 1950-6945 1294-9361 |
DOI: | 10.1684/epd.2013.0568 |
Popis: | Hypohidrosis is an uncommon and reversible side effect of topiramate treatment, reported mainly in children. This report presents an adult patient with complex partial seizures who was treated with topiramate and developed hypohidrosis coupled with hyperthermia, related to high environmental temperature and physical exercise. Reduced sweat response was confirmed using the Neuropad test. Signs and symptoms ceased after drug discontinuation. During topiramate treatment, it is important to recognise this side effect, although the exact causal mechanism has not yet been clarified. |
Databáze: | OpenAIRE |
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