Aortic Elastic Properties and Myocardial Performance Index Are Impaired in Patients with Lichen Planus
| Autor: | Engin Bozkurt, Telat Keleş, Elcin Ozdemir, Mehmet Erdoğan, Cemal Koseoglu, Ahmet Göktuğ Ertem, Tahir Durmaz, O Kurmus, Gulsen Akoglu, G Koseoglu, Akın Aktaş |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Cardiac output Tei index Aortic Diseases Aortic elastic properties 030204 cardiovascular system & hematology 030207 dermatology & venereal diseases 03 medical and health sciences Vascular Stiffness 0302 clinical medicine Diabetes mellitus medicine.artery Internal medicine Linear regression medicine Humans Myocardial performance index Cardiac Output Original Paper Aorta business.industry Lichen Planus General Medicine Middle Aged medicine.disease Surgery Blood pressure medicine.anatomical_structure Echocardiography Ventricle Cardiology Female Cardiomyopathies business Body mass index Student's t-test |
| Zdroj: | Medical Principles and Practice |
| ISSN: | 1423-0151 1011-7571 |
| DOI: | 10.1159/000443478 |
| Popis: | Objectives: The aim of this study was to investigate the elastic properties of the aorta and the myocardial performance index of the left ventricle (LV) in patients with lichen planus (LP). Subjects and Methods: A total of 54 patients with LP and 50 controls were enrolled in the study. The 2 groups were well-matched regarding age, gender, body mass index, any smoking history, diabetes mellitus and systolic and diastolic blood pressure (SBP and DBP). The echocardiographic examination was performed on the study subjects and the controls. Aortic elasticity parameters and the myocardial performance index of the LV were calculated. The Student t test, the χ2 test and multiple linear regression were used for the statistical analysis. Results: Aortic strain (AS, 4.77 ± 1.81 vs. 8.95 ± 2.22; p < 0.001) and aortic distensibility (AD, 0.25 ± 0.009 vs. 0.42 ± 0.120; p < 0.001) were significantly lower, and aortic stiffness index β (ASIβ, 3.65 ± 1.03 vs. 2.70 ± 0.91; p < 0.001) was significantly higher in the LP group than in the controls. The myocardial performance index (Tei index) was significantly higher in the LP group than in the control group (p = 0.001). The duration of the LP was negatively correlated with AS (r = -0.364, p < 0.001) and AD (r = -0.279, p = 0.006), and positively correlated with the Tei index (r = 0.324, p = 0.001) and ASIβ (r = 0.364, p < 0.001). After adjustment for relevant confounders (age, male gender, smoking, SBP, DBP, diabetes mellitus and low- and high-density lipoprotein cholesterol), LP and its duration were still associated with AS, AD and ASIβ. Conclusion: In this study, AS and AD were lower and ASIβ and myocardial performance index higher in LP patients than in controls. |
| Databáze: | OpenAIRE |
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