Modeling and optimization of bioactive compounds from chickpea seeds (Cicer arietinum L)

Autor: Ivana Lj. Nikolic, Tatjana Kundaković, Ivan M. Savic, Ivana Savic-Gajic
Rok vydání: 2018
Předmět:
Zdroj: Solid State Ionics
ISSN: 1520-5754
0149-6395
Popis: The aim of study was to model and optimize the extraction of polyphenols and flavonoids with expressed antioxidant activity from chickpea seeds using a central composite design. The optimal extraction conditions were the extraction time of 145.5 min, ethanol concentration of 83.7% and liquid-to-solid ratio of 24.9 (expressed as cm(3) per g). The content of total polyphenol and flavonoid was 2.75 g gallic acid equivalent per kilogram of the dried extract and 0.147 g rutin equivalent per kilogram of the dried extract, respectively. Using 2,2-diphenyl-1-picrylhydrazyl assay, it was found that the optimal extract had the IC50 of 1.55 mg cm(-3).
Databáze: OpenAIRE