Diurnal Variation in the Direction of Mood Switches in Patients With Rapid-Cycling Bipolar Disorder

Autor: Susana Feldman-Naim, Ellen Leibenluft, Erick H. Turner
Rok vydání: 1997
Předmět:
Zdroj: The Journal of Clinical Psychiatry. 58:79-84
ISSN: 0160-6689
Popis: Background: We assessed diurnal variation in the direction of mood switches in a sample of outpatients with rapid-cycling bipolar disorder who were on stable medication regimens. We predicted that patients would be more likely to switch from depression into mania or hypomania during the daytime hours and from mania/hypomania into depression overnight. Method: Fifteen patients with rapid-cycling bipolar disorder completed self-rated mood scales twice a day: once shortly after awakening and once at bedtime. Using 3 months of data for each patient, we performed categorical analyses (McNemar chi-square) to study the direction of mood switches between each day's morning and evening rating and between each evening rating and the subsequent morning rating. Results: As predicted, switches that occurred between the morning and evening ratings were more likely to be from depression into mania/ hypomania or euthymia (64.3%) than in the opposite direction (35.6%; p
Databáze: OpenAIRE