European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease
| Autor: | M. N. Khalil, J. B. van der Schoot, A. Bischof-Delaloye, A. Lowry, R. Fridrich, E. Inglese, Michael N. Maisey |
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| Rok vydání: | 1990 |
| Předmět: |
Male
Technetium Tc 99m Sestamibi medicine.medical_specialty Ischemia chemistry.chemical_element Contrast Media Perfusion scanning Coronary Disease Technetium Sensitivity and Specificity Isotopes of technetium Coronary artery disease Internal medicine Technetium-99 Nitriles medicine Humans Radiology Nuclear Medicine and imaging cardiovascular diseases Radionuclide Imaging business.industry Heart General Medicine Organotechnetium Compounds Middle Aged medicine.disease Europe Thallium Radioisotopes medicine.anatomical_structure chemistry Cardiology Thallium Female business Nuclear medicine Artery |
| Zdroj: | European journal of nuclear medicine. 16(12) |
| ISSN: | 0340-6997 |
| Popis: | Fifty-six patients in Europe were entered into a multi-centre study to compare the accuracy of technetium 99m methoxyisobutylisonitrile (99mTc-MIBI) for the detection of coronary artery disease (CAD) with thallium 201 (201Tl) chloride perfusion scanning. The results showed a high degree of concordance between the two radiopharmaceuticals. Some 81% (678/840) of myocardial segments showed the same result (normal, infarct or ischaemia), and 80% (45/56) of patients had the same diagnosis. Overall detection of CAD in patients was 98% for 201T1 and 96% for 99mTc-MIBI. Detection of CAD in total arteries was 68% for both agents. In this study 99mTc-MIBI was as accurate as 201Tl for the detection of coronary artery stenoses. |
| Databáze: | OpenAIRE |
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