Immune response of prostatic cancer patients to cytomegalovirus-infected and -transformed human cells
| Autor: | Anna Marie Laychock, Edgar J. Sanford, Fred Rapp, Laszlo Geder |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Male
Cancer Research Antibodies Neoplasm Prostatic Hyperplasia Congenital cytomegalovirus infection Cytomegalovirus In Vitro Techniques Antibodies Viral Cell Line Immune system Antigen Antigens Neoplasm Neoplasms medicine Humans Antigens Viral Aged Carcinoma Transitional Cell Urinary bladder business.industry Prostatic Neoplasms virus diseases Cancer Middle Aged Hyperplasia medicine.disease Cell Transformation Neoplastic medicine.anatomical_structure Transitional cell carcinoma Urinary Bladder Neoplasms Oncology Immunology Humoral immunity business |
| Zdroj: | Cancer. 42:1766-1771 |
| ISSN: | 1097-0142 0008-543X |
| DOI: | 10.1002/1097-0142(197810)42:4<1766::aid-cncr2820420415>3.0.co;2-o |
| Popis: | The indirect immunofluorescent test was used to determine the prevalence of humoral immunity to cytomegalovirus (CMV)-induced antigens in prostatic cancer patients as compared to age-matched controls. Significantly more prostatic cancer patients demonstrated high CMV-antibody titers than did the benign prostatic hyperplasia and nonurogenital cancer groups; however, no significant difference in reactivity was found between paients with prostatic cancer and transitional cell carcinoma of the urinary bladder. When screened against CMV-transformed human cell lines, the reactivity of the sera followed the rate of expression of CMV-related antigens of cell lines used in these tests. |
| Databáze: | OpenAIRE |
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