Implementation and Operational Research
| Autor: | Sharon Kapambwe, Mulindi H. Mwanahamuntu, Vikrant V. Sahasrabuddhe, Victor Mudenda, Meridith Blevins, Carla J. Chibwesha, Krista S. Pfaendler, Bryan E. Shepherd, Sten H. Vermund, Jeffrey S. A. Stringer, Groesbeck P. Parham, Michael L. Hicks |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
medicine.medical_specialty Population Uterine Cervical Neoplasms Zambia HIV Infections Logistic regression Risk Assessment Article Acquired immunodeficiency syndrome (AIDS) medicine Humans Pharmacology (medical) education Cervical cancer Gynecology education.field_of_study business.industry Age Factors virus diseases Odds ratio medicine.disease Confidence interval Infectious Diseases Female Serostatus business Risk assessment Demography |
| Zdroj: | JAIDS Journal of Acquired Immune Deficiency Syndromes. 70:e20-e26 |
| ISSN: | 1525-4135 |
| DOI: | 10.1097/qai.0000000000000685 |
| Popis: | BACKGROUND: Cervical cancer screening efforts linked to HIV/AIDS care programs are being expanded across sub-Saharan Africa. Evidence on the age distribution and determinants of invasive cervical cancer (ICC) cases detected in such programs is limited. METHODS: We analyzed program operations data from the Cervical Cancer Prevention Program in Zambia the largest public sector programs of its kind in sub-Saharan Africa. We examined age distribution patterns by HIV serostatus of histologically confirmed ICC cases and used multivariable logistic regression to evaluate independent risk factors for ICC among younger ( 35 years) women. RESULTS: Between January 2006 and April 2010 of 48626 women undergoing screening 571 (1.2%) were diagnosed with ICC including 262 (46%) HIV seropositive (median age: 35 years) 131 (23%) HIV seronegative (median age: 40 years) and 178 (31%) of unknown HIV serostatus (median age: 38 years). Among younger ( |
| Databáze: | OpenAIRE |
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