A Review of Malaria Diagnostic Tools: Microscopy and Rapid Diagnostic Test (RDT)
Autor: | Mazie J. Barcus, Walther H. Wernsdorfer, Awalludin Sutamihardja, Chansuda Wongsrichanalai, Sinuon Muth |
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Rok vydání: | 2007 |
Předmět: |
Microscopy
medicine.medical_specialty Rapid diagnostic test Malaria vaccine business.industry Drug resistance medicine.disease Diagnostic tools Azure Stains Giemsa stain Malaria Surgery Diagnosis of malaria Infectious Diseases Drug development Virology parasitic diseases medicine Humans Parasitology Intensive care medicine business Reagent Strips |
Zdroj: | The American Journal of Tropical Medicine and Hygiene. 77:119-127 |
ISSN: | 1476-1645 0002-9637 |
Popis: | The absolute necessity for rational therapy in the face of rampant drug resistance places increasing importance on the accuracy of malaria diagnosis. Giemsa microscopy and rapid diagnostic tests (RDTs) represent the two diagnostics most likely to have the largest impact on malaria control today. These two methods, each with characteristic strengths and limitations, together represent the best hope for accurate diagnosis as a key component of successful malaria control. This review addresses the quality issues with current malaria diagnostics and presents data from recent rapid diagnostic test trials. Reduction of malaria morbidity and drug resistance intensity plus the associated economic loss of these two factors require urgent scaling up of the quality of parasite-based diagnostic methods. An investment in anti-malarial drug development or malaria vaccine development should be accompanied by a parallel commitment to improve diagnostic tools and their availability to people living in malarious areas. |
Databáze: | OpenAIRE |
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