Atheroembolic renal disease and membranous nephropathy, in a patient with myelodysplastic syndrome, eosinophilia, and trisomy 8
| Autor: | Dimitra Rontoianni, Sotsiou F, John Apostolidis, T. Apostolou, Constantinos Pappas, Nikoletta Nikolopoulou |
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| Rok vydání: | 2002 |
| Předmět: |
Male
Pathology medicine.medical_specialty Biopsy Trisomy Trisomy 8 Glomerulonephritis Membranous Membranous nephropathy hemic and lymphatic diseases Eosinophilia medicine Humans Relapsing polychondritis Transplantation business.industry Glomerulonephritis Middle Aged medicine.disease Nephrology Myelodysplastic Syndromes medicine.symptom Vasculitis business Chromosomes Human Pair 8 Kidney disease |
| Zdroj: | Nephrology Dialysis Transplantation. 17:1336-1338 |
| ISSN: | 1460-2385 |
| DOI: | 10.1093/ndt/17.7.1336 |
| Popis: | Atheroembolic renal disease (ARD) is an important and often misdiagnosed cause of renal failure. It usually occurs in adult patients suffering from atherosclerosis and is a result of embolization of cholesterol crystals from atheromatous plaques, in small sized arteries causing ischaemia of the tissues affected. Acute renal failure of variable severity, at times irreversible, accompanies this disorder [1]. A common laboratory finding, in 70–80% of the cases, is eosinophilia, usually mild [1]. However, eosinophilia can rarely be an expression of a myelodysplastic syndrome (MDS) [2]. Furthermore, in a small percentage of patients with MDS, a variety of autoimmune or paraneoplasmatic disorders, like relapsing polychondritis, vasculitis syndromes, etc., coexist with this haematological process, with glomerulonephritis being a rare association [3]. A 61-year-old patient is described and discussed thoroughly. The patient had ARD, membranous nephropathy and MDS with eosinophilia, and trisomy 8 of bone marrow cells coexisted. |
| Databáze: | OpenAIRE |
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