Outcomes following intra-amniotic instillation with indigo carmine to diagnose prelabor rupture of membranes in singleton pregnancies: a single center experience
| Autor: | Henry Adekola, Sharif Sakr, David Bryant, Navleen Gill, Eleazar Soto, Jacques S. Abramowicz, Deslyn T.G. Hobson |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Fetal Membranes Premature Rupture medicine.medical_specialty Amniotic fluid Gestational Age Prom Indigo Carmine Chorioamnionitis Injections Young Adult 03 medical and health sciences 0302 clinical medicine Pregnancy 030225 pediatrics Funisitis medicine Humans Rupture of membranes Amnion Coloring Agents Retrospective Studies Gynecology 030219 obstetrics & reproductive medicine Interleukin-6 Obstetrics business.industry Ureaplasma Infections Pregnancy Outcome Obstetrics and Gynecology Gestational age Amniotic Fluid medicine.disease Premature birth Pediatrics Perinatology and Child Health Premature Birth Female business Ureaplasma urealyticum |
| Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 29:544-549 |
| ISSN: | 1476-4954 1476-7058 |
| Popis: | To evaluate clinical outcomes of women with singleton pregnancies that underwent intra-amniotic dye instillation (amniodye test) following equivocal diagnosis of prelabor rupture of membranes (PROM).Records of 34 pregnant women who underwent amniodye test for equivocal PROM were reviewed. Comparisons of characteristics, amniotic fluid (AF) cultures, AF interleukin (IL)-6 concentrations, and placenta pathology results between women who tested positive and those who tested negative were performed. A sub-analysis of women who were amniodye test-negative was also performed.(1) Commonest indication for amniodye test was a typical history of PROM with positive conventional tests and persistently normal AF volume, (2) amniodye test-positive women had a shorter procedure-to-delivery interval (p = 0.008), and a greater proportion of histologic acute chorioamnionitis (p = 0.04) and funisitis (p = 0.01) than amniodye-negative women, and (3) in addition to similarities to women with amniodye-positive test, amniodye test-negative women who delivered34 weeks, had a greater proportion of women with risk for preterm birth (p = 0.04), than their counterparts who delivered between 34 0/7 and 36 6/7 weeks.Equivocal diagnosis of PPROM should warrant an amniodye test to avoid iatrogenic intervention in women with intact amniotic membranes. AF analysis should be performed in amniodye test-negative women. |
| Databáze: | OpenAIRE |
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