Does CMV infection impact the virulence ofEnterococcus faecalis?
Autor: | Justyna Gołębiewska, Jacek M. Witkowski, Alicja Dębska-Ślizień, Tomasz Jarzembowski, Bolesław Rutkowski, Agnieszka Daca |
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Rok vydání: | 2013 |
Předmět: |
Microbiology (medical)
Virulence Factors medicine.medical_treatment Immunology Virulence Microbiology Enterococcus faecalis Immunocompromised Host enterococci medicine Humans Letter to the Editor Gram-Positive Bacterial Infections Immunodeficiency Kidney transplantation biology Coinfection CMV RTx Immunosuppression biology.organism_classification medicine.disease Kidney Transplantation ASA gene Transplantation Infectious Diseases Enterococcus Cytomegalovirus Infections Microbial Interactions Parasitology |
Zdroj: | Virulence |
ISSN: | 2150-5608 2150-5594 |
DOI: | 10.4161/viru.26315 |
Popis: | Renal transplant (RTx) recipients are at a high risk of infection caused by commensal bacteria. Apart from immunodeficiency resulting from the use of immunosuppression, RTx patients often suffer from various urological malformations, increasing susceptibility to infections.1,2 In the early phase after renal transplantation, when patients are exposed to the most intense immunosuppression and enterococcal infections are most common, even life-threatening infections can present with mild or virtually no clinical symptoms.1,2 Difficulties in managing enterococcal infections result from the fact that this bacteria as a commensal may not be eradicated due to prophylaxis. On the other hand, there is growing evidence that Enterococcus spp., which is usually considered harmless commensal, can cause serious infections.3 It seems crucial to identify patients most susceptible to UTIs, especially recurrent, symptomatic infections.2 |
Databáze: | OpenAIRE |
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