Epidemiology and Clinical Characteristics of Presumed Ocular Histoplasmosis in Olmsted County, Minnesota
Autor: | Timothy T. Xu, Margaret M. Reynolds, Wendy M. Smith, David O. Hodge |
---|---|
Rok vydání: | 2023 |
Předmět: |
medicine.medical_specialty
Presumed ocular histoplasmosis syndrome Minnesota education Endothelial Growth Factors Histoplasmosis Article 03 medical and health sciences 0302 clinical medicine Histoplasma Epidemiology medicine Immunology and Allergy Humans Retrospective Studies 030203 arthritis & rheumatology biology business.industry Incidence (epidemiology) bacterial infections and mycoses medicine.disease biology.organism_classification Dermatology Choroidal Neovascularization Ophthalmology Choroidal neovascularization 030221 ophthalmology & optometry medicine.symptom business Eye Infections Fungal |
Zdroj: | Ocul Immunol Inflamm |
ISSN: | 1744-5078 |
Popis: | PURPOSE: To describe the incidence, prevalence, and clinical characteristics of presumed ocular histoplasmosis syndrome (POHS) in a Histoplasma endemic region. METHODS: The International Classification of Diseases, 9(th) and 10(th) Revision codes were used to search the Rochester Epidemiology Project, a record-linkage system for medical care provided in Olmsted County, MN. Medical records were reviewed to confirm POHS diagnoses in county residents from January 1, 2006 to December 31, 2015. Age- and sex-adjusted incidence rates were calculated and adjusted to the 2010 U.S. White population. RESULTS: There were 18 incident cases (30 eyes) and 87 prevalent cases (131 eyes). The incidence rate was 1.35 per 100,000 per year. The mid-study prevalence rate was 0.064%. Choroidal neovascularization (CNV) occurred in 17.4% of affected eyes. At last follow-up, 16.8% of affected eyes had POHS-related decreased VA ( |
Databáze: | OpenAIRE |
Externí odkaz: |