Late Onset Nephrogenic Systemic Fibrosis in a Patient with Stage 3 Chronic Kidney Disease: a Case Report
| Autor: | Joo Hark Yi, Jisun Bang, Young-Sun Ko, Yu Jeong Lim, Hyun Min Seo, Mi Yeon Yu, Sang-Woong Han, Woon Yong Jung |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Late onset Case Report Gastroenterology 03 medical and health sciences 0302 clinical medicine Internal medicine Chronic Kidney Disease Medicine Medical history 030212 general & internal medicine Nephrogenic Systemic Fibrosis Stage (cooking) Gadolinium-based Contrast Agents medicine.diagnostic_test business.industry General Medicine medicine.disease Nephrology Nephrogenic systemic fibrosis Skin biopsy Combined therapy Methotrexate business medicine.drug Kidney disease |
| Zdroj: | Journal of Korean Medical Science |
| ISSN: | 1598-6357 1011-8934 |
| Popis: | Nephrogenic systemic fibrosis (NSF) is a progressive systemic fibrosing disease that may occur after gadolinium contrast exposure. It can lead to severe complications and even death. NSF is highly prevalent among patients with advanced chronic kidney disease (CKD). In this report, however, we describe the case of a patient with NSF that occurred during early CKD. A 65-year-old man with stage 3a CKD was transferred to our hospital because of lower extremity edema. The medical history revealed that he was exposed to gadolinium 185 days earlier, and the result of his tibial skin biopsy was consistent with NSF. The patient underwent a combined therapy with ultraviolet-A1 phototherapy and methotrexate and steroid therapy for 6 months. The combined therapy stopped the systemic progression of NSF. Graphical Abstract |
| Databáze: | OpenAIRE |
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