Differential expression of genes coding for ribosomal proteins in different human tissues
| Autor: | Chiara Romualdi, Stefania Bortoluzzi, Fabio d’Alessi, Gian Antonio Danieli |
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| Rok vydání: | 2001 |
| Předmět: |
Adult
Ribosomal Proteins Statistics and Probability Ovary Biology Biochemistry Ribosomal protein Ribosomal protein genes Gene expression medicine Humans Differential expression Molecular Biology Gene Expressed Sequence Tags Gene Expression Profiling Skeletal muscle Molecular biology Computer Science Applications Computational Mathematics medicine.anatomical_structure Gene Expression Regulation Computational Theory and Mathematics Expression data Data Interpretation Statistical Databases Nucleic Acid |
| Zdroj: | Bioinformatics. 17:1152-1157 |
| ISSN: | 1367-4811 1367-4803 |
| DOI: | 10.1093/bioinformatics/17.12.1152 |
| Popis: | Motivation: To perform a computational and statistical study on a large set of gene expression data pertaining six adult human tissues (brain, liver, skeletal muscle, ovary, retina and uterus) for analyzing the expression of ribosomal protein genes. Results: Unexpectedly, in each of the considered tissues large variations in the expression of ribosomal protein genes were observed. Moreover, when comparing the expression levels of 89 ribosomal protein genes in six different tissues, 13 genes appeared differentially expressed among tissues. Avalilability: The expression data of the ribosomal protein genes together with supplementary material (complete transcriptional profiles of the considered human tissues) are freely available at the site GETProfiles (http://telethon.bio.unipd.it/GETProfiles/). Contact: danieli@bio.unipd.it * To whom all correspondence should be addressed. |
| Databáze: | OpenAIRE |
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