Laryngeal vibration as a non-invasive neuromodulation therapy for spasmodic dysphonia
| Autor: | George S. Goding, Jürgen Konczak, Peter Watson, Arash Mahnan, Joshua E Aman, Sanaz Khosravani, I-Ling Yeh, Yang Zhang |
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| Rok vydání: | 2019 |
| Předmět: |
Larynx
Adult Male medicine.medical_specialty Voice Quality lcsh:Medicine Neurophysiology Sensory system Pilot Projects Audiology Spasmodic dysphonia Vibration Article 03 medical and health sciences 0302 clinical medicine Cortex (anatomy) otorhinolaryngologic diseases Medicine Humans Speech Cervical dystonia lcsh:Science 030223 otorhinolaryngology Physical Therapy Modalities Aged Multidisciplinary Proprioception business.industry lcsh:R Focal dystonia Middle Aged medicine.disease Dysphonia Neuromodulation (medicine) Dystonia medicine.anatomical_structure Voice Feasibility Studies Motor cortex lcsh:Q Female medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Scientific Reports Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019) |
| ISSN: | 2045-2322 |
| Popis: | Spasmodic dysphonia (SD) is an incurable focal dystonia of the larynx that impairs speech and communication. Vibro-tactile stimulation (VTS) alters afferent proprioceptive input to sensorimotor cortex that controls speech. This proof-of-concept study examined the effect of laryngeal VTS on speech quality and cortical activity in 13 SD participants who vocalized the vowel /a/ while receiving VTS for 29 minutes. In response to VTS, 9 participants (69%) exhibited a reduction of voice breaks and/or a meaningful increase in smoothed cepstral peak prominence, an acoustic measure of voice/speech quality. Symptom improvements persisted for 20 minutes past VTS. Application of VTS induced a significant suppression of theta band power over the left somatosensory-motor cortex and a significant rise of gamma rhythm over right somatosensory-motor cortex. Such suppression of theta oscillations is observed in patients with cervical dystonia who apply effective sensory tricks, suggesting that VTS in SD may activate a similar neurophysiological mechanism. Results of this feasibility study indicate that laryngeal VTS modulates neuronal synchronization over sensorimotor cortex, which can induce short-term improvements in voice quality. The effects of long-term VTS and its optimal dosage for treating voice symptoms in SD are still unknown and require further systematic study. |
| Databáze: | OpenAIRE |
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