The effect of chlorpromazine on plasma renin activity and aldosterone in man
| Autor: | David Robertson, Andrew M. Michelakis |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Adult
medicine.medical_specialty Supine position Time Factors Chlorpromazine Endocrinology Diabetes and Metabolism Clinical Biochemistry Posture Blood Pressure Aldosterone levels Pharmacology Biochemistry Plasma renin activity chemistry.chemical_compound Endocrinology Internal medicine Renin medicine Humans In patient Aldosterone business.industry Biochemistry (medical) Blood pressure chemistry Injections Intravenous Schizophrenia Normal sodium business medicine.drug |
| Zdroj: | The Journal of clinical endocrinology and metabolism. 41(06) |
| ISSN: | 0021-972X |
| Popis: | The response of plasma renin activity (PRA) and aldosterone to the intravenous administration of chlorpromazine was determined in schizophrenic patients while they were supine and on a normal sodium diet. In all subjects PRA and aldosterone increased during chlorpromazine administration with little or no change in blood pressure. The maximum PRA and aldosterone levels occurred 60 min after the higher dose of chlorpromazine. These data suggest that chlorpromazine affects the renin-angiotensin-aldosterone system and it may interfere with the evaluation of this system in patients receiving this drug. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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