Cost-effectiveness of using an extensively hydrolyzed casein formula containing Lactobacillus rhamnosus GG in managing infants with cow's milk allergy in the US
| Autor: | Gary Neidich, Roger H. Kobayashi, Vinay Mehta, Julian F. Guest |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Cost effectiveness Cost-Benefit Analysis Milk allergy law.invention Decision Support Techniques 03 medical and health sciences Probiotic 0302 clinical medicine Lactobacillus rhamnosus law Cow's milk allergy 030225 pediatrics Casein Nutramigen medicine Humans 030212 general & internal medicine Food science Chelating Agents biology business.industry Lacticaseibacillus rhamnosus Probiotics food and beverages Caseins Infant General Medicine medicine.disease biology.organism_classification Infant Formula United States Female Milk Hypersensitivity business |
| Zdroj: | Current medical research and opinion. 34(9) |
| ISSN: | 1473-4877 |
| Popis: | To estimate the cost-effectiveness of using an extensively hydrolyzed casein formula containing the probiotic Lactobacillus rhamnosus GG (eHCF + LGG; Nutramigen LGG) compared with an eHCF alone and an amino acid formula (AAF) in treating cow's milk allergy (CMA) in the US, from the perspective of third-party insurers and from parents.A decision model was used to estimate the probability of cow's milk allergic infants developing tolerance to cow's milk by 18 months. The model also estimated the cost to insurers and parents (US dollars at 2016 prices) of managing infants over 18 months after starting one of the formulae, as well as the relative cost-effectiveness of each of the formulae.The probability of developing tolerance to cow's milk was higher among infants who were fed eHCF + LGG compared with those fed an eHCF alone or an AAF. Infants who are initially fed with eHCF + LGG are expected to utilize fewer healthcare resources than those fed with one of the other formulae. Hence, the estimated total healthcare cost incurred by third-party insurers and parents of initially feeding infants with eHCF + LGG was less than that of feeding infants with an eHCF alone or an AAF.Initial management of newly-diagnosed cow's milk allergic infants with eHCF + LGG was found to afford a cost-effective strategy to both third-party insurers and parents when compared to an eHCF alone or an AAF. |
| Databáze: | OpenAIRE |
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