Alterations in calcium metabolism in cancer patients treated with 6-diazo-5-oxo-L-norleucine
| Autor: | W. P. Laird Myers, Magill G |
|---|---|
| Rok vydání: | 1956 |
| Předmět: |
Calcium metabolism
medicine.medical_specialty business.industry Diazooxonorleucine Cancer Neoplasms therapy Water-Electrolyte Balance medicine.disease 6-Diazo-5-oxo-L-norleucine General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound Endocrinology Hypercalcuria chemistry Leucine Internal medicine Neoplasms medicine Calcium business |
| Zdroj: | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 93(2) |
| ISSN: | 0037-9727 |
| Popis: | SummaryTen patients with hypercalcemia and hypercalcuria and 1 patient with normocalcemia and hypercalcuria were treated with 6-diazo-5-oxo-L-norleucine alone or in combination with 6-mercaptopurine. Full correction of hypercalcemia with treatment occurred in 8 of 13 instances in these patients. Correction of hypercalcuria was observed in 9 of 14 instances. Various possible mechanisms underlying these observed effects are considered. |
| Databáze: | OpenAIRE |
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