Role of the kidney in fibrinolytic activity of blood
| Autor: | H.A. Dewar, I. Sudhakaran Menon, D.J Newell |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
Adult
Heart Defects Congenital Male medicine.medical_specialty Adolescent Kidney Renal Veins Fibrinolytic Agents Internal medicine Papaverine medicine Humans business.industry Fibrinolysis Rheumatic Heart Disease General Medicine Middle Aged medicine.anatomical_structure Endocrinology Liver Cardiology Arterial blood Female business Plasminogen activator medicine.drug |
| Zdroj: | Lancet (London, England). 1(7546) |
| ISSN: | 0140-6736 |
| Popis: | A considerable increase of fibrinolytic activity in renal-vein blood, as compared with arterial blood, was found in 31 patients with rheumatic valvular heart-disease or congenital heart-disease—in every case without any signs of congestive cardiac failure. In each of 13 patients in whom circulation through the kidney was accelerated by intravenous injection of papaverine, fibrinolytic activity increased. It is suggested that human kidneys make a very significant contribution of plasminogen activator to the circulation of the body by supplying quantities greater than those removed in the liver and that these amounts are determined by the rate of renal blood-flow. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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