The behavioral and psychological symptoms of dementia in Down syndrome (BPSD-DS) scale : comprehensive assessment of psychopathology in Down syndrome
| Autor: | Dekker, Alain D., Sacco, Silvia, Carfi, Angelo, Benejam, Bessy, Vermeiren, Yannick, Beugelsdijk, Gonny, Schippers, Mieke, Hassefras, Lyanne, Eleveld, José, Grefelman, Sharina, Fopma, Roelie, Bomer-Veenboer, Monique, Botí, M. Ángeles, Oosterling, G. Danielle E., Scholten, Esther, Tollenaere, Marleen, Checkley, Laura, Strydom, André, Van Goethem, Gert, Onder, Graziano, Blesa, Rafael, zu Eulenburg, Christine, Coppus, Antonia, Rebillat, Anne-Sophie, Fortea, Juan, De Deyn, Peter Paul, Universitat Autònoma de Barcelona |
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| Přispěvatelé: | Life Course Epidemiology (LCE), Molecular Neuroscience and Ageing Research (MOLAR) |
| Rok vydání: | 2018 |
| Předmět: |
Male
MILD COGNITIVE IMPAIRMENT Trisomy 21 Down syndrome Psychological intervention Behavioral Symptoms Disease Neuropsychological Tests Severity of Illness Index 0302 clinical medicine NEUROPSYCHIATRIC INVENTORY Apathy BPSD 030212 general & internal medicine Observer Variation General Neuroscience General Medicine Middle Aged Alzheimer's disease Neuropsychiatric symptoms trisomy 21 Psychiatry and Mental health Clinical Psychology INTELLECTUAL DISABILITIES Anxiety Female medicine.symptom Alzheimer’s disease Research Article Clinical psychology Psychopathology Adult DIAGNOSTIC-CRITERIA ALZHEIMER-DISEASE-CONSORTIUM Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18] Interviews as Topic 03 medical and health sciences All institutes and research themes of the Radboud University Medical Center medicine Humans Dementia Aged Behavior Aggression business.industry behavior Reproducibility of Results PSYCHIATRIC-SYMPTOMS NATURAL-HISTORY ADULTS medicine.disease INDIVIDUALS Cross-Sectional Studies neuropsychiatric symptoms Human medicine Geriatrics and Gerontology business MALADAPTIVE BEHAVIORS 030217 neurology & neurosurgery dementia |
| Zdroj: | Dipòsit Digital de Documents de la UAB Universitat Autònoma de Barcelona Journal of Alzheimer’s Disease, 63(2), 797-819. IOS Press Journal of Alzheimer's Disease, 63(2), 797-820 Journal of Alzheimer's disease Journal of Alzheimer's Disease, 63, 2, pp. 797-819 Journal of Alzheimer's Disease, 63, 797-819 Journal of Alzheimer's Disease Journal of Alzheimer's Disease 63 (2018) 2 Dekker, A D, Sacco, S, Carfi, A, Benejam, B, Vermeiren, Y, Beugelsdijk, G, Schippers, M, Hassefras, L, Eleveld, J, Grefelman, S, Fopma, R, Bomer-veenboer, M, Boti, M, Oosterling, G D E, Scholten, E, Tollenaere, M, Checkley, L, Strydom, A, Van Goethem, G, Onder, G, Blesa, R, Zu Eulenburg, C, Coppus, A M W, Rebillat, A, Fortea, J & De Deyn, P P 2018, ' The Behavioral and Psychological Symptoms of Dementia in Down Syndrome (BPSD-DS) Scale : Comprehensive Assessment of Psychopathology in Down Syndrome ', Journal of Alzheimer's Disease, vol. 63, no. 2, pp. 797-819 . https://doi.org/10.3233/JAD-170920 JOURNAL OF ALZHEIMERS DISEASE r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau instname |
| ISSN: | 1875-8908 1387-2877 |
| DOI: | 10.3233/JAD-170920 |
| Popis: | People with Down syndrome (DS) are prone to develop Alzheimer's disease (AD). Behavioral and psychological symptoms of dementia (BPSD) are core features, but have not been comprehensively evaluated in DS. In a European multidisciplinary study, the novel Behavioral and Psychological Symptoms of Dementia in Down Syndrome (BPSD-DS) scale was developed to identify frequency and severity of behavioral changes taking account of life-long characteristic behavior. 83 behavioral items in 12 clinically defined sections were evaluated. The central aim was to identify items that change in relation to the dementia status, and thus may differentiate between diagnostic groups. Structured interviews were conducted with informants of persons with DS without dementia (DS, n = 149), with questionable dementia (DS+Q, n = 65), and with diagnosed dementia (DS+AD, n = 67). First exploratory data suggest promising interrater, test-retest, and internal consistency reliability measures. Concerning item relevance, group comparisons revealed pronounced increases in frequency and severity in items of anxiety, sleep disturbances, agitation & stereotypical behavior, aggression, apathy, depressive symptoms, and eating/drinking behavior. The proportion of individuals presenting an increase was highest in DS+AD, intermediate in DS+Q, and lowest in DS. Interestingly, among DS+Q individuals, a substantial proportion already presented increased anxiety, sleep disturbances, apathy, and depressive symptoms, suggesting that these changes occur early in the course of AD. Future efforts should optimize the scale based on current results and clinical experiences, and further study applicability, reliability, and validity. Future application of the scale in daily care may aid caregivers to understand changes, and contribute to timely interventions and adaptation of caregiving. |
| Databáze: | OpenAIRE |
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