Altered antioxidant enzyme profile in wound healing

Autor:	Saraswati L. Udupa, Shivananda Nayak, Laxminarayana Udupa
Rok vydání:	2003
Předmět:	chemistry.chemical_classification Antioxidant biology medicine.medical_treatment Glutathione peroxidase Clinical Biochemistry Glutathione reductase Lysyl oxidase Pharmacology Article Enzyme Biochemistry chemistry Catalase Ultimate tensile strength biology.protein medicine Wound healing
Zdroj:	Indian Journal of Clinical Biochemistry. 18:75-79
ISSN:	0974-0422 0970-1915
DOI:	10.1007/bf02867669
Popis:	The effects of the alcoholic extract of the flowers ofIxora coccinea were studied on some of the antioxidant enzymes in dead space wounds created in rats. Increases in the tensile strength of the wound and in the level of lysyl oxidase, the crucial enzyme for collagen maturation, were observed indicating a definite prohealing action. In addition, a highly significant increase in the levels of catalase, glutathione peroxidase and glutathione reductase was observed in the drug-treated group. Thus, the gain in tensile strength may be attributed not only to the better cross-linking but also to the antioxidant properties of the drug.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f8906d266cd4eb4828354178b016ab https://doi.org/10.1007/bf02867669 Zobrazit plný text záznamu Full text from SpringerLink