Tubular and glomerular function in children after renal transplantation
| Autor: | N Bar-Nathan, Amit Dagan, Roxana Cleper, Vladislav Smolkin, Bella Eisenstein, Irit Krause, Miriam Davidovits |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Graft Rejection
Male medicine.medical_specialty Adolescent Renal glomerulus Urology Renal function Excretion chemistry.chemical_compound Postoperative Complications Internal medicine medicine Humans Child Acute tubular necrosis Transplantation Creatinine Analysis of Variance business.industry Acidosis Renal Tubular Kidney Tubular Necrosis Acute medicine.disease Kidney Transplantation Endocrinology Kidney Tubules chemistry Renal physiology Pediatrics Perinatology and Child Health Urinary Tract Infections Urine osmolality Drug Therapy Combination Female business Immunosuppressive Agents Glomerular Filtration Rate |
| Zdroj: | Pediatric transplantation. 9(4) |
| ISSN: | 1397-3142 |
| Popis: | Glomerular and tubular function of transplanted kidneys were assessed in 46 children aged 15.7 +/- 4.6 yr, 4.2 +/- 2.8 yr after renal transplantation. There were 34 cadaveric, and 12 living-related donors. Twelve patients (26%) had acute episodes (acute tubular necrosis, rejection, or urinary tract infection) during follow-up. All patients were on triple immunosuppression. The mean serum creatinine was 1.5 +/- 0.6 mg/dL. Creatinine clearance (Ccreat) calculated from a 24-h urine collection was 48.0 +/- 19.7 mL/min/1.73 m(2), and that estimated from the Schwartz formula, 61.0 +/- 22.5 mL/min/1.73 m(2). A positive correlation was found between the calculated and estimated clearances. Mean urine concentrating ability was 487 +/- 184 mOsmol/kg, with a value lower than 400 mOsmol/kg in 35% of patients. There was a positive correlation between urine osmolality and estimated Ccreat. Metabolic acidosis (bicarbonate |
| Databáze: | OpenAIRE |
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