Implementation of the Frequency Scatter Index in Clinical Commercially Available Double-pass Systems
| Autor: | Luis Issolio, Roberto Sánchez, Joan A Martínez‐roda, Carlos E. García-Guerra, Aníbal G de Paul, Jaume Pujol |
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| Přispěvatelé: | Universitat Politècnica de Catalunya. Centre de Desenvolupament de Sensors, Instrumentació i Sistemes, Universitat Politècnica de Catalunya. Departament d'Òptica i Optometria, Universitat Politècnica de Catalunya. GREO - Grup de Recerca en Enginyeria Òptica |
| Rok vydání: | 2021 |
| Předmět: |
Index (economics)
genetic structures Light Residual Spearman's rank correlation coefficient Intraocular scattering Cataract Retina Cellular and Molecular Neuroscience Optics Imatge Tècniques d' Imaging systems Humans Scattering Radiation Sensitivity (control systems) Ciències de la visió::Òptica física::Llum [Àrees temàtiques de la UPC] Adaptive optics Frequency Scatter index Vision Ocular Mathematics business.industry Scattering Cataracts Wavefront sensor Ciències de la salut::Medicina::Oftalmologia [Àrees temàtiques de la UPC] eye diseases Sensory Systems Ophthalmology Full width at half maximum Cataractes Objective scatter index Double-pass system business |
| Zdroj: | UPCommons. Portal del coneixement obert de la UPC Universitat Politècnica de Catalunya (UPC) |
| ISSN: | 1460-2202 |
| Popis: | A previous work has reported a methodology to quantify intraocular scattering using a high sensitivity double-pass instrument with a robust index, the frequency scatter index. The purpose of our study was to evaluate an adaptation of the frequency scatter index for use in clinical double-pass systems. A prospective observational study was carried out in a group of patients with nuclear cataracts (n = 52) and in a control group (n = 11) using conventional double-pass systems. The frequency scatter index and the objective scatter index were used to assess the scattering. The Spearman coefficient was calculated to assess the correlation between both indexes, obtained from the double-pass images. Simultaneous measurements were performed with a double-pass and with a Hartmann-Shack wavefront sensor in the control group. The root-mean-square wavefront error and the full width at half maximum of the double-pass image were used to quantify the residual aberrations introduced by the variations in pupil size and retinal eccentricity. Measurement in eyes with different grades of cataracts shows a strong correlation (¿ = 0.929, p < .0001) between the frequency scatter index and the objective scatter index. A certain degree of correlation was observed between the objective scatter index and the root-mean-square and between the objective scatter index and the full width at half maximum, both for measurements with a different pupillary diameter and with a different retinal eccentricity (p < .05). No relationship was observed between the frequency scatter index and the root-mean-square or between the frequency scatter index and the full width at half maximum (p > .05). We have introduced and evaluated an adaptation of a methodology proposed recently for the measurement of intraocular scattering using the double-pass technique with a robust index, which is less affected by ocular aberrations. The frequency scatter index can be applied to conventional double-pass instruments available in clinical environments. |
| Databáze: | OpenAIRE |
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