Inherited anaemias: sickle cell and thalassaemia

Autor:	Rachel Kesse-Adu, Jo Howard
Rok vydání:	2021
Předmět:	Genetics Red Cell business.industry Cell Disease General Medicine medicine.disease Dehydrogenase deficiency Red cell enzyme Hereditary spherocytosis Cell membrane medicine.anatomical_structure Haemolytic anaemias Immunology medicine Abnormality business
Zdroj:	Medicine. 49:210-216
ISSN:	1357-3039
DOI:	10.1016/j.mpmed.2021.01.006
Popis:	Inherited haemolytic anaemias are caused by a genetic mutation that results in an abnormality within the red cell leading to its early destruction. This abnormality can affect the cell membrane (e.g. hereditary spherocytosis), result from an absence or abnormality of a red cell enzyme (e.g. glucose-6-phosphate dehydrogenase deficiency) or affect haemoglobin, leading to a haemoglobinopathy such as sickle cell disease or thalassaemia.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ea9df12df8329fa68c76b6154e96a8 https://doi.org/10.1016/j.mpmed.2021.01.006 Zobrazit plný text záznamu Full Text from ScienceDirect