Differential Contraction of Large and Small Chromosomes in Cultured Leucocytes of Man

Autor:	P.H. Fitzgerald
Rok vydání:	1965
Předmět:	Chromosome 7 (human) Genetics Biology Molecular biology Chromosomes Tissue Culture Techniques Chromosome 17 (human) Chromosome 4 Chromosome 16 Chromosome 3 Chromosome 18 Leukocytes Molecular Biology Small supernumerary marker chromosome Cell Division Genetics (clinical) Chromosome 12
Zdroj:	Cytogenetic and Genome Research. 4:65-73
ISSN:	1424-859X 1424-8581
DOI:	10.1159/000129844
Popis:	The summed lengths of chromosomes Nos. 1 and 2 (x) were compared with the summed lengths of the small acrocentric chromosomes, Nos. 21, 22 and in males the Y chromosome (z), in 10 cells from each of 10 males and 5 females. Both chromosome groups varied in length together, but the changes were proportionally less in the small acrocentric chromosomes than in the large chromosomes. This was the case in both sexes. The relative changes in chromosome length were expressed by the regression coefficients z = 0.1461 x + 5.55 in males and z = 0.1077x + 4.32 in females. It was considered that this differential contraction might be peculiar to the stage of chromosome contraction examined and that compensatory contraction occurred at other stages, or, on the other hand, that the greater degree of contraction of the large chromosomes involved an additional order of chromosome coiling.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e68ca96a458b1c62757511144d1e86 https://doi.org/10.1159/000129844 Zobrazit plný text záznamu