| Autor: |
Robin Detering, Eleonora G. Karthaus, Wernard A.A. Borstlap, Corrie A.M. Marijnen, Cornelis J.H. van de Velde, Willem A. Bemelman, Geerard L. Beets, Pieter J. Tanis, Arend G.J. Aalbers, A.G.J. Aalbers, Y. Acherman, G.D. Algie, B. Alting von Geusau, F. Amelung, T.S. Aukema, I.S. Bakker, S.A. Bartels, S. Basha, A.J.N.M. Bastiaansen, E. Belgers, W. Bleeker, J. Blok, R.J.I. Bosker, J.W. Bosmans, M.C. Boute, N.D. Bouvy, H. Bouwman, A. Brandt-Kerkhof, D.J. Brinkman, S. Bruin, E.R.J. Bruns, J.P.M. Burbach, J.W.A. Burger, C.J. Buskens, S. Clermonts, P.P.L.O. Coene, C. Compaan, E.C.J. Consten, T. Darbyshire, S.M.L. de Mik, E.J.R. de Graaf, I. de Groot, RJ de Vos tot Nederveen Cappel, J.H.W. de Wilt, J. van der Wolde, FC den Boer, J.W.T. Dekker, A. Demirkiran, M. Derkx-Hendriksen, F.R. Dijkstra, P. van Duijvendijk, M.S. Dunker, Q.E. Eijsbouts, H. Fabry, F. Ferenschild, J.W. Foppen, E.J.B. Furnee, M.F. Gerhards, P. Gerven, J.A.H. Gooszen, J.A. Govaert, W.M.U. Van Grevenstein, R. Haen, J.J. Harlaar, E. van der Harst, K. Havenga, J. Heemskerk, J.F. Heeren, B. Heijnen, P. Heres, C. Hoff, W. Hogendoorn, P. Hoogland, A. Huijbers, P. Janssen, A.C. Jongen, F.H. Jonker, E.G. Karthaus, A. Keijzer, J.M.A. Ketel, J. Klaase, F.W.H. Kloppenberg, M.E. Kool, R. Kortekaas, P.M. Kruyt, J.T. Kuiper, B. Lamme, J.F. Lange, T. Lettinga, D.J. Lips, F. Logeman, M.F. Lutke Holzik, E. Madsen, A. Mamound, C.C. Marres, I. Masselink, M. Meerdink, A.G. Menon, J.S. Mieog, D. Mierlo, G.D. Musters, G.A.P. Nieuwenhuijzen, P.A. Neijenhuis, J. Nonner, M. Oostdijk, S.J. Oosterling, P.M.P. Paul, K.C.M.J. Peeters, I.T.A. Pereboom, F. Polat, P. Poortman, M. Raber, B.M.M. Reiber, R.J. Renger, C.C. van Rossem, H.J. Rutten, A. Rutten, R. Schaapman, M. Scheer, L. Schoonderwoerd, N. Schouten, A.M. Schreuder, W.H. Schreurs, G.A. Simkens, G.D. Slooter, H.C.E. Sluijmer, N. Smakman, R. Smeenk, H.S. Snijders, D.J.A. Sonneveld, B. Spaansen, EJ Spillenaar Bilgen, E. Steller, W.H. Steup, C. Steur, E. Stortelder, J. Straatman, H.A. Swank, C. Sietses, H.A. Groen, HG ten Hoeve, WW ter Riele, I.M. Thorensen, B. Tip-Pluijm, B.R. Toorenvliet, L. Tseng, J.B. Tuynman, J. van Bastelaar, S.C. van Beek, A.W.H. van de Ven, M.A.J. van de Weijer, C. van den Berg, I. van den Bosch, J.D.W. van der Bilt, S.J. van der Hagen, R. van der Hul, G. van der Schelling, A. van der Spek, N. van der Wielen, E. van Duyn, C. van Eekelen, J.A. van Essen, K. van Gangelt, A.A.W. van Geloven, C. van Kessel, Y.T. van Loon, A. van Rijswijk, S.J. van Rooijen, T. van Sprundel, L. van Steensel, W.F. van Tets, H.L. van Westreenen, S. Veltkamp, T. Verhaak, P.M. Verheijen, L. Versluis-Ossenwaarde, S. Vijfhuize, W.J. Vles, S.C. Voeten, F.J. Vogelaar, W.W. Vrijland, E. Westerduin, M.E. Westerterp, M. Wetzel, K.P. Wevers, B. Wiering, C.D.M. Witjes, M.W. Wouters, S.T.K. Yauw, E.S. van der Zaag, E.C. Zeestraten, D.D.E. Zimmerman, T. Zwieten |
| Přispěvatelé: |
Robotics and image-guided minimally-invasive surgery (ROBOTICS), Surgery, Amsterdam Reproduction & Development (AR&D), Amsterdam Gastroenterology Endocrinology Metabolism, Graduate School, AGEM - Digestive immunity, AGEM - Re-generation and cancer of the digestive system, CCA - Cancer Treatment and Quality of Life, AGEM - Endocrinology, metabolism and nutrition, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
EJSO, 45(11), 2059-2069. ELSEVIER SCI LTD
European Journal of Surgical Oncology, 45, 2059-2069
European Journal of Surgical Oncology, 45, 11, pp. 2059-2069
Detering, R, Karthaus, E G, Borstlap, W A A, Marijnen, C A M, van de Velde, C J H, Bemelman, W A, Beets, G L, Tanis, P J, Aalbers, A G J & Dutch Snapshot Research Group 2019, ' Treatment and survival of locally recurrent rectal cancer: A cross-sectional population study 15 years after the Dutch TME trial ', European Journal of Surgical Oncology, vol. 45, no. 11, pp. 2059-2069 . https://doi.org/10.1016/j.ejso.2019.06.016
European Journal of Surgical Oncology, 45(11), 2059-2069. W.B. Saunders Ltd
European journal of surgical oncology, 45(11), 2059-2069. W.B. Saunders Ltd
EJSO-European Journal of Surgical Oncology, 45(11), 2059-2069. ELSEVIER SCI LTD |
| ISSN: |
0748-7983 |
| Popis: |
Introduction: Optimized treatment of primary rectal cancer might have influenced treatment characteristics and outcome of locally recurrent rectal cancer (LRRC). Subgroup analysis of the Dutch TME trial showed that preoperative radiotherapy (PRT) for the primary tumour was an independent poor prognostic factor after diagnosis of LRRC. This cross-sectional population study aimed to evaluate treatment and overall survival (OS) of LRRC patients, stratified for prior preoperative radiotherapy (PRT) and intention of treatment of LRRC.Methods: All patients developing LRRC were selected from a collaborative Snapshot study on 2095 surgically treated rectal cancer patients from 71 Dutch hospitals in the year 2011. Cox proportional hazard analysis was performed to determine predictors for OS.Results: A total of 107 LRRC patients (5.1%) were included, of whom 88 (82%) underwent PRT for their primary tumour. LRRC was treated with initial curative intent in 31 patients (29%), with eventual resection in 20 patients (19%). Median OS was 22 and 8 months after curative and palliative intent treatment, respectively (p Conclusions: This cross-sectional study revealed that rectal cancer patients, who underwent curative resection in the Netherlands in 2011 and subsequently developed local recurrence, were amenable for again curative intent treatment in 29%, with a corresponding median survival of 22 months. Prior PRT was not significantly associated with survival after diagnosis of LRRC. (C) 2019 Elsevier Ltd, BASO similar to The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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Full Text from ScienceDirect 