Lower Systolic Blood Pressure and Cardiovascular Event Risk Stratified by Renal Resistive Index in Hospitalized Cardiovascular Patients: J-VAS Study
| Autor: | Satoshi Hoshide, Takahiro Komori, Praew Kotruchin, Hiromi Ueno, Kazuomi Kario |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Acute coronary syndrome Time Factors Systole Blood Pressure 030204 cardiovascular system & hematology Kidney Risk Assessment 03 medical and health sciences 0302 clinical medicine Japan Risk Factors Internal medicine Internal Medicine medicine Humans 030212 general & internal medicine Risk factor Stroke Aged Retrospective Studies Inpatients business.industry Incidence Hazard ratio Ultrasonography Doppler Middle Aged Prognosis medicine.disease Blood pressure Quartile Cardiovascular Diseases Heart failure Disease Progression Cardiology Arterial stiffness Female Vascular Resistance business human activities Follow-Up Studies |
| Zdroj: | American Journal of Hypertension. 32:365-374 |
| ISSN: | 1941-7225 0895-7061 |
| Popis: | BACKGROUND The threshold of blood pressure (BP) reduction in cardiovascular patients is debatable due to the J-shaped curve phenomenon, which is particularly observed in patients with increased arterial stiffness. The renal resistive index (RRI) correlates well with systemic arterial stiffness; therefore, we aimed to demonstrate the role of RRI in guiding the choice of optimal BP. METHODS A retrospective analysis of prospectively collected data of the hospitalized cardiovascular patients at Jichi Medical University Hospital. All patients had the RRI measurement performed and were assigned to a higher (RRI ≥ 0.8) or lower RRI group. Each group was subdivided by quartiles of the BP at discharge. The primary endpoints were fatal and nonfatal cardiovascular events, including heart failure, acute coronary syndrome, acute aortic disease, acute arterial occlusion, and stroke. RESULTS The mean follow-up period was 1.9 years (3,365 person-years), n = 1,777 (mean age 64.7 years). There were 252 cardiovascular events occurred, 24.0% and 12.2% in the higher and lower RRI populations, P < 0.001. In the higher RRI group, the lowest systolic BP (SBP) quartile ( CONCLUSIONS Lower SBP at discharge was associated with a risk of cardiovascular events in the hospitalized cardiovascular patients with RRI ≥ 0.8. |
| Databáze: | OpenAIRE |
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