Recent advances in transdermal drug delivery systems: a review
| Autor: | Woo Yeup Jeong, Mina Kwon, Hye Eun Choi, Ki Su Kim |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Drug
Computer science media_common.quotation_subject Characterization Biomedical Engineering Medicine (miscellaneous) 02 engineering and technology Review 010402 general chemistry 01 natural sciences Critical discussion Biomaterials Characterization methods Transdermal drug delivery Medical technology Active/passive method R855-855.5 Transdermal media_common Skin Alternative methods Skin care 021001 nanoscience & nanotechnology 0104 chemical sciences Drug concentration Risk analysis (engineering) Ceramics and Composites 0210 nano-technology |
| Zdroj: | Biomaterials Research, Vol 25, Iss 1, Pp 1-15 (2021) Biomaterials Research |
| ISSN: | 2055-7124 |
| Popis: | Various non-invasive administrations have recently emerged as an alternative to conventional needle injections. A transdermal drug delivery system (TDDS) represents the most attractive method among these because of its low rejection rate, excellent ease of administration, and superb convenience and persistence among patients. TDDS could be applicable in not only pharmaceuticals but also in the skin care industry, including cosmetics. Because this method mainly involves local administration, it can prevent local buildup in drug concentration and nonspecific delivery to tissues not targeted by the drug. However, the physicochemical properties of the skin translate to multiple obstacles and restrictions in transdermal delivery, with numerous investigations conducted to overcome these bottlenecks. In this review, we describe the different types of available TDDS methods, along with a critical discussion of the specific advantages and disadvantages, characterization methods, and potential of each method. Progress in research on these alternative methods has established the high efficiency inherent to TDDS, which is expected to find applications in a wide range of fields. |
| Databáze: | OpenAIRE |
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