Quantitative Sensory Testing in adults with Tourette syndrome
| Autor: | Odette Schunke, Daniel Schöttle, Ursula Kahl, Wiebke Grashorn, Patrick Haggard, Ulrike Bingel, Christos Ganos, Alexander Münchau |
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| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Sensory phenomena Adult Male medicine.medical_specialty Tics media_common.quotation_subject Medizin Sensory system Audiology Tourette syndrome 03 medical and health sciences Young Adult 0302 clinical medicine Sensory threshold Perception Surveys and Questionnaires medicine Humans Young adult media_common medicine.disease body regions 030104 developmental biology Neurology Case-Control Studies Sensory Thresholds Neuropathic pain Sensation Disorders Female Neurology (clinical) Geriatrics and Gerontology medicine.symptom Psychology Neuroscience 030217 neurology & neurosurgery Tourette Syndrome |
| Zdroj: | Parkinsonismrelated disorders. 24 |
| ISSN: | 1873-5126 |
| Popis: | Introduction Abnormal sensory perceptions, for instance hypersensitivity to certain external stimuli or premonitory urges preceding tics, are core features in Gilles de la Tourette syndrome (GTS). Aberrant awareness of externally applied stimuli in terms of altered sensory perception thresholds might contribute to these sensory phenomena in GTS. Methods We used the well-established and standardized “Quantitative Sensory Testing” (QST) battery (German Research Network on Neuropathic Pain) to investigate 13 sensory parameters including thermal, mechanical/tactile and pain thresholds in 14 GTS patients without clinically significant comorbidities and 14 healthy controls matched for age and gender. Results There were no relevant group differences in any of the 13 QST parameters and no specific QST pattern in GTS patients. There was no correlation between QST parameters and “Premonitory Urge for Tics scale” (PUTS) scores. Conclusion Our data show that the perceptual threshold detection of externally applied sensory stimuli is normal in adults with GTS. This indicates that other perceptual mechanisms, such as abnormal central sensorimotor processing and/or aberrant interoceptive awareness might underlie the clinically significant sensory abnormalities in GTS. |
| Databáze: | OpenAIRE |
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