Protein Shape Retrieval Contest
Autor: | Florent, Langenfeld, Apostolos, Axenopoulos, Halim, Benhabiles, Petros, Daras, Giachetti, Andrea, Xusi, Han, Karim, Hammoudi, Daisuke, Kihara, Lai, Tuan M., Haiguang, Liu, Mahmoud, Melkemi, Mylonas, Stelios K., Genki, Terashi, Yufan, Wang, Feryal, Windal, Matthieu, Montes |
---|---|
Rok vydání: | 2019 |
Předmět: | |
DOI: | 10.2312/3dor.20191058 |
Popis: | This track aimed at retrieving protein evolutionary classification based on their surfaces meshes only. Given that proteins are dynamic, non-rigid objects and that evolution tends to conserve patterns related to their activity and function, this track offers a challenging issue using biologically relevant molecules. We evaluated the performance of 5 different algorithms and analyzed their ability, over a dataset of 5,298 objects, to retrieve various conformations of identical proteins and various conformations of ortholog proteins (proteins from different organisms and showing the same activity). All methods were able to retrieve a member of the same class as the query in at least 94% of the cases when considering the first match, but show more divergent when more matches were considered. Last, similarity metrics trained on databases dedicated to proteins improved the results. Eurographics Workshop on 3D Object Retrieval SHREC Session 1 25 31 Florent Langenfeld, Apostolos Axenopoulos, Halim Benhabiles, Petros Daras, Andrea Giachetti, Xusi Han, Karim Hammoudi, Daisuke Kihara, Tuan M. Lai, Haiguang Liu, Mahmoud Melkemi, Stelios K. Mylonas, Genki Terashi, Yufan Wang, Feryal Windal, and Matthieu Montes |
Databáze: | OpenAIRE |
Externí odkaz: |