Estrogen synthesis in castrated women: the action of human chorionic gonadotropin and corticotropin
| Autor: | Joseph J. Smith, Seymour L. Romney, Aaron Poliak, David Friedlander |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
Adult
endocrine system medicine.medical_specialty Estrone Urinary system Population Chorionic Gonadotropin Human chorionic gonadotropin Adrenocorticotropic Hormone Internal medicine Adrenal Glands Medicine Endocrine system Vaginal smear Humans Castration education 17-Hydroxycorticosteroids Vaginal Smears education.field_of_study Estradiol business.industry Estriol Obstetrics and Gynecology Estrogens Castrated Female Stimulation Chemical 17-Ketosteroids Endocrinology Female business Genital Diseases Female hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | American journal of obstetrics and gynecology. 110(3) |
| ISSN: | 0002-9378 |
| Popis: | This study was carried out to correlate changes in urinary estrogens and the response of the adrenal glands to administration of human chorionic gonadotropin (HCG) and acetocorticotropic hormone (ACTH) in 5 castrated female volunteers. A total of 50,000 U. of HCG was administered intramuscularly to each. Two weeks later, each received a total of 120 U. of gel of ACTH intramuscularly. Vaginal smears and urinary hormone assays were done before and after treatment. Administration of HCG did not produce any changes in urinary hormone levels or in vaginal smears. ACTH produced increases in 24 hour urinary 17-ketosteroids, 17-hydroxycorticoids, and total estrogens, with a shift to the right in the maturation index of the vaginal smear. |
| Databáze: | OpenAIRE |
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