The antitumoral activity of some derivatives of 6-aminochrysene

Autor:	Henri Tagnon, Ronal Rosso, Nguyen P Buu-Hoi, André Coune, M. Gautier, Sylvio Garattini, Georges G. Lambelin
Rok vydání:	1970
Předmět:	Mammary tumor Chemistry Mammary Neoplasms Experimental Antineoplastic Agents General Medicine Phenanthrenes Pharmacology medicine.disease Rats Mice Rhabdomyosarcoma medicine Carcinoma Animals Female 6-aminochrysene Sarcoma Carcinoma Ehrlich Tumor Sarcoma 180
Zdroj:	European Journal of Cancer (1965). 6:81-87
ISSN:	0014-2964
DOI:	10.1016/0014-2964(70)90005-8
Popis:	Twenty-two N-substituted derivatives of the carcinostatic 6-aminochrysene have been tested as potential carcinostatic agents (using 6-aminochrysene as a standard) on spontaneous mammary tumor in [C3H/020] F1 mice, and on the slow-growing transplanted rhabdomyosarcoma in inbred WAG/Rij rats. Many of these compounds displayed important activity against both types of tumor, and some of them merit further investigations. In contrast compounds active on these experimental tumors, were completely inactive on Ehrlich carcinoma and on Sarcoma 180.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c885dd14544d1cdc5e30296b867813 https://doi.org/10.1016/0014-2964(70)90005-8 Zobrazit plný text záznamu