Clinical manifestation of acute cerebral infarcts in multiple arterial territories
| Autor: | Anna Therese Bjerkreim, Annette Fromm, Vojtech Novotny, Lars Thomassen, Nicola Logallo, Christopher Elnan Kvistad, Ulrike Waje-Andreassen, Sander Johan Aarli, Andrej Netland Khanevski, Halvor Naess |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Neurosciences. Biological psychiatry. Neuropsychiatry Clinical manifestation neurological manifestation Lateralization of brain function Brain Ischemia Behavioral Neuroscience Internal medicine medicine Humans Cerebral infarcts Stroke Retrospective Studies Original Research multiple stroke medicine.diagnostic_test symptoms and signs business.industry Total anterior circulation infarct diffusion‐weighted imaging Magnetic resonance imaging Cerebral Infarction Partial anterior circulation infarct medicine.disease Diffusion Magnetic Resonance Imaging Cardiology business Diffusion MRI RC321-571 |
| Zdroj: | e2296 Brain and Behavior Brain and Behavior, Vol 11, Iss 8, Pp n/a-n/a (2021) |
| Popis: | Objectives We aimed to assess frequencies and radiological aspects of single‐ and multiterritory clinical manifestation among patients with acute cerebral infarcts in multiple arterial territories (MACI). Materials & methods We retrospectively reviewed admission records and diffusion‐weighted magnetic resonance imaging of patients with MACI admitted to our stroke unit between 2006 and 2017. MACI was defined as acute cerebral ischemic lesions in at least two out of three arterial cerebral territories, that is, the left anterior, right anterior and the bilateral posterior territory. Patients with single‐ and multiterritory clinical manifestation were then compared for topographical distribution of the ischemic lesions, the number of ischemic lesions, and The Oxfordshire Community Stroke Project classification. Results Out of 311 patients with MACI, 222 (71.4%) presented with single‐territory clinical manifestation. Involvement of the left hemisphere (OR = 0.37, 95% CI 0.16–0.82), less than five ischemic lesions (OR = 0.58, 95% CI 0.35–0.97), and partial anterior circulation infarct clinical stroke syndrome (OR = 0.57, 95% CI 0.34–0.97) were associated with single‐territory clinical manifestation. Involvement of all three territories (OR = 2.58, 95% = 1.48–4.50), more than 10 ischemic lesions (OR = 2.30, 95% CI 1.32–4.01) and total anterior circulation infarct clinical stroke syndrome (OR = 3.31, 95% CI 1.39–7.86) were associated with multiterritory clinical manifestation. Conclusion Most patients with MACI present with single‐territory clinical manifestation on admission. Diffusion‐weighted magnetic resonance imaging is therefore necessary for a definite diagnosis. We aimed to assess frequencies and radiological aspects of single‐ and multi‐territory clinical manifestation among patients with acute cerebral infarcts in multiple arterial territories (MACI). The results show that most patients with MACI present with single‐territory clinical manifestation on admission. Diffusion‐weighted magnetic resonance imaging is therefore necessary for definite diagnosis. |
| Databáze: | OpenAIRE |
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