Preparation of 2,3-diaminopropionate from ring opening of aziridine-2-carboxylate

Autor:	Hyun-Joon Ha, Hyo Jae Yoon, Yongeun Kim, Min Sung Kim, Seung Whan Ko, Won Koo Lee, Kyusung Han, Hoseop Yun
Rok vydání:	2005
Předmět:	chemistry.chemical_compound Aqueous solution Nucleophile Chemistry Organic Chemistry Drug Discovery Polymer chemistry Organic chemistry General Medicine Azide Ring (chemistry) Biochemistry Aziridine-2-carboxylate
Zdroj:	Tetrahedron Letters. 46:4407-4409
ISSN:	0040-4039
Popis:	Ring opening reaction of an enantiomerically pure aziridine-2-carboxylate with an azide nucleophile under aqueous acidic media proceeded efficiently and stereoselectively to give 3-amino-2-azidopropionate which is converted to orthogonally protected 2,3-diaminopropionate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c52209de2e97f1a280a10faca2b1d4 https://doi.org/10.1016/j.tetlet.2005.04.039 Zobrazit plný text záznamu Full Text from ScienceDirect