Inspiratory airflow dynamics during sleep in veterans with Gulf War illness: a controlled study
| Autor: | Avram R. Gold, Joan E. Broderick, Mohammad M. Amin, Morris S. Gold, Zuzana Belisova, Sayeed Hossain |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty Supine position Polysomnography Polysomnogram Asymptomatic Diagnosis Differential Reference Values Sleep and breathing medicine Humans Persian Gulf Syndrome health care economics and organizations Veterans Sleep Apnea Obstructive medicine.diagnostic_test business.industry Sleep apnea Middle Aged medicine.disease humanities respiratory tract diseases Inhalation Otorhinolaryngology Anesthesia Physical therapy Breathing Neurology (clinical) medicine.symptom Arousal business Body mass index |
| Zdroj: | Sleep and Breathing. 15:333-339 |
| ISSN: | 1522-1709 1520-9512 |
| DOI: | 10.1007/s11325-010-0386-8 |
| Popis: | To determine whether veterans with Gulf War Illness (GWI) are distinguished by sleep-disordered breathing, we compared inspiratory airflow dynamics during sleep between veterans with GWI and asymptomatic veterans of the first Gulf War. We recruited 18 male veterans with GWI and 11 asymptomatic male veterans of the first Gulf War by advertisement. The two samples were matched for age and body mass index. Each participant underwent a first full-night polysomnogram (PSG) while sleeping supine using standard clinical monitoring of sleep and breathing. A second PSG was performed measuring airflow with a pneumotachograph in series with a nasal mask and respiratory effort with a supraglottic pressure (Psg) catheter to assess the presence of inspiratory airflow limitation during supine N2 sleep. We determined the prevalence of flow-limited breaths by sampling continuous N2 sleep and plotting inspiratory flow against Psg for each breath in the sample. We expressed the prevalence of flow-limited breaths as their percentage in the sample. Compared to controls, veterans with GWI had an increased frequency of arousals related to apneas, hypopneas, and mild inspiratory airflow limitation. During supine N2 sleep, veterans with GWI had 96 ± 5% (mean ± SD) of their breaths flow-limited while controls had 36 ± 25% of their breaths flow limited (p |
| Databáze: | OpenAIRE |
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