Dematiaceous Fungal Sinusitis
| Autor: | Richard D. Kopke, Larry A. Zieske, Randy Hamill |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
Male medicine.medical_specialty Antifungal Agents Adolescent 03 medical and health sciences 0302 clinical medicine Recurrence Paranasal Sinuses medicine Humans Combined Modality Therapy Sinusitis 030223 otorhinolaryngology Mri scan Sinus (anatomy) Retrospective Studies Dematiaceous business.industry Retrospective cohort study medicine.disease Fungal sinusitis medicine.anatomical_structure Mycoses Otorhinolaryngology 030220 oncology & carcinogenesis Female Surgery Mitosporic Fungi Radiology Tomography X-Ray Computed business Complication |
| Zdroj: | Otolaryngology–Head and Neck Surgery. 105:567-577 |
| ISSN: | 1097-6817 0194-5998 |
| Popis: | Six cases of dematiaceous fungal sinusitis are reported, together with a review of 33 other cases collated from a review of the English literature. The sinusitis was more often unilateral vs. bilateral. A characteristic serpiginous hyperdense intrasinus opacification, as well as sinus expansion with bone erosion, was often seen on CT scan. MRI scan showed lucent sinus cavities on T1 and T2 weighting. A comparison of surgical treatment vs. surgery with systemic antifungal therapy revealed decreased recurrence and complication statistics in the combined therapy group. There was a trend toward increased recurrence/persistence and complications associated with invasive histologic findings and only surgical treatment, but not statistically significant. At the present time, we recommend comprehensive surgical treatment followed by systemic antifungal therapy, though clinical judgment and individualization should occur. Future studies are planned to further define the disease entity and its therapy. |
| Databáze: | OpenAIRE |
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