The use of rigorous methods was strongly warranted among prognostic prediction models for obstetric care
| Autor: | Wen Wang, Guolin He, Jing Tan, Qiao He, Xinghui Liu, Xin Sun, Yiquan Xiong, Yana Qi, Guiting Zhang, Chunrong Liu, Meng Chen |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Blinding Epidemiology Obstetric Surgical Procedures Specialty Prognostic prediction Outcome assessment Model validation Obstetric care 03 medical and health sciences 0302 clinical medicine Pregnancy Surveys and Questionnaires Outcome Assessment Health Care Humans Medicine 030212 general & internal medicine business.industry Models Theoretical Prognosis Research Design Family medicine Female business 030217 neurology & neurosurgery Statistician |
| Zdroj: | Journal of Clinical Epidemiology. 115:98-105 |
| ISSN: | 0895-4356 |
| Popis: | Objective The objective of the study was to examine methodological characteristics about the design and conduct in prognostic prediction models used for obstetric care. Study Design and Setting We searched PubMed for studies on prognostic prediction models for obstetric care, published in top general medicine or major specialty journals between January 2011 and February 2018. Teams of method-trained investigators independently screened titles and abstracts and collected data using a prespecified, pilot-tested, structured questionnaire. Results In total, 91 studies were eligible, of which two were published in top general medicine journals, 20 (22.0%) involved an epidemiologist or statistician, 18 (19.4%) published study protocols, 53 (58.2%) did not include any model validation, 20 (22.0%) did not clearly state the intended timing of use, 23 (25.3%) had no eligibility criteria, 15 (16.5%) did not use clear criteria for ascertaining outcome, and 69 (75.82%) did not apply blinding to outcome assessment. Among those models, 11 (12.1%) included participants fewer than 200 events, 41 (48.8%) had fewer than 100 events, and 19 (24.7%) had fewer than 10 events per variable. Conclusion The prognostic prediction models have important limitations in design and conduct. Substantial efforts are needed to strengthen the production of reliable prognostic prediction models for obstetric care. |
| Databáze: | OpenAIRE |
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