Hearing Loss in Mucopolysaccharidosis
| Autor: | Emília Katiane Embiruçu de Araújo Leão, Cibele Gomes Bicalho, Álvaro Muiños de Andrade, Angelina Xavier Acosta |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Pediatrics Hearing loss medicine.medical_treatment Mucopolysaccharidosis otorhinolaryngology Physical examination inborn errors of metabolism Disease 03 medical and health sciences 0302 clinical medicine medicine otorhinolaryngologic diseases In patient Original Research 030304 developmental biology hearing loss 030203 arthritis & rheumatology 0303 health sciences Rehabilitation medicine.diagnostic_test business.industry mucopolysaccharidosis medicine.disease Conductive hearing loss Otorhinolaryngology RF1-547 Medicine medicine.symptom business metabolism |
| Zdroj: | International Archives of Otorhinolaryngology v.25 n.3 2021 International Archives of Otorhinolaryngology Fundação Otorrinolaringologia (FORL) instacron:FORL International Archives of Otorhinolaryngology, Vol 25, Iss 03, Pp e386-e391 (2021) International Archives of Otorhinolaryngology, Volume: 25, Issue: 3, Pages: 386-391, Published: 13 SEP 2021 |
| Popis: | Introduction Mucopolysaccharidosis (MPS) is a set of rare diseases caused by deficiency of lysosomal enzymes that lead to the accumulation of glycosaminoglycans (GAG) in tissues and organs, which, in turn, is responsible for the multisystemic clinical, chronic, and progressive symptoms. Objective To describe the profile of the otorhinolaryngological clinical examination and audiology tests of patients with MPS disease. Methods The present study is a case series. The evaluation was performed, initially, in 24 patients with MPS types I, II, IIIA, IV and VI. Results The most common hearing complaint was hearing loss, which was confirmed by audiology tests in almost 100% of the patients, most of whom presented conductive hearing loss. Conclusions It is important to evaluate the complaints, physical examination, and audiology tests in patients with MPS. The otorhinolaryngologistshould be part of the group of professionals that follows these patients to better monitor their hearing and provide early hearing rehabilitation. |
| Databáze: | OpenAIRE |
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