Enhanced Podophyllotoxin Production fromAgrobacterium RhizogenesTransformed Cultures ofPodophyllum Hexandrum
| Autor: | Archana Giri, Dhingra, Narasu Ml, C. C. Giri |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Hplc analysis
Guanine Plants Medicinal Time Factors biology Agrobacterium fungi Podophyllum biology.organism_classification Transformation Genetic Podophyllotoxin Seeds Botany medicine Molecular Medicine Cells Cultured Chromatography High Pressure Liquid Rhizome Cell Line Transformed New Zealand Rhizobium medicine.drug |
| Zdroj: | Natural Product Letters. 15:229-235 |
| ISSN: | 1057-5634 |
| DOI: | 10.1080/10575630108041286 |
| Popis: | Podophyllotoxin, a potent chemotherapeutic agent is obtained from Podophylhum hexandrum Royle. Embryos of P. hexandrum were transformed using different strains of Agrobacterium rhizogenes viz. A4, 15834, K599. Transformed nature of the calli was ascertained and the cultures were further maintained as individual clones. HPLC analysis of transformed cultures depicted a three-fold increase in podophyllotoxin content in comparison to controls. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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