ENCAPSULATION OF MYXOBOLUS PENDULA (MYXOSPORIDIA) BY EPITHELIOID CELLS OF ITS CYPRINID HOST SEMOTILUS ATROMACULATUS
Autor: | Patricia Romans, Anne Koehler, Maurice J. Ringuette, Sherwin S. Desser |
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Rok vydání: | 2004 |
Předmět: |
Gills
Semotilus atromaculatus Spores Protozoan Cyprinidae DNA Ribosomal Fish Diseases Cytokeratin Microscopy Electron Transmission Animals Parasite hosting Intermediate filament Protozoan Infections Animal In Situ Hybridization Ecology Evolution Behavior and Systematics biology Histocytochemistry Epithelioid Cells fungi Eukaryota Anatomy biology.organism_classification Immunohistochemistry Molecular biology Spore Myxobolus Parasitology Interdigitating Cells DNA Probes Epithelioid cell |
Zdroj: | Journal of Parasitology. 90:1401-1405 |
ISSN: | 1937-2345 0022-3395 |
Popis: | Spores of Myxobolus pendula develop within the cores of complex cysts on the gill arch of creek chub Semotilus atromaculatus. Adjacent to, and surrounding, the spores are concentric layers of stratified interdigitating cells, whose nature was examined by transmission electron microscopy and by immunohistochemical and molecular biological techniques. In situ hybridization data using parasite-derived ribosomal DNA as a probe indicate that infection leads to the encapsulation of developing plasmodia by host immune cells that form an epithelioid granuloma. Epithelioid cell-cell adhesion is effected by desmosomes anchored intracellularly to cytokeratin intermediate filaments. High levels of alkaline phosphatase activity are associated with regions of cellular interdigitation. The granuloma may serve to limit the spread of the parasite to surrounding tissues but does not appear to inhibit diffusion of oxygen and nutrients to the developing spores. |
Databáze: | OpenAIRE |
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