Unusual Case of Combined Gliomeningeal Heterotopia on the Nose of an Infant
| Autor: | Nathan T. Harvey, Shyan Vijayasekaran, Anna Schauer, Benjamin A. Wood |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Pathology
medicine.medical_specialty Dermatology Choristoma Pathology and Forensic Medicine 030207 dermatology & venereal diseases 03 medical and health sciences Meninges 0302 clinical medicine Nose Diseases otorhinolaryngologic diseases medicine Humans neoplasms Primary Cutaneous Meningioma Nose Nasal glioma Unusual case business.industry Infant General Medicine respiratory system medicine.disease nervous system diseases Nasal glial heterotopia Heterotopia (medicine) medicine.anatomical_structure 030220 oncology & carcinogenesis business Neuroglia |
| Zdroj: | The American Journal of Dermatopathology. 40:515-518 |
| ISSN: | 0193-1091 |
| Popis: | Nasal glial heterotopia ("nasal glioma") and cutaneous heterotopic meningeal nodules ("primary cutaneous meningioma") are rare congenital lesions characterized by the presence of heterotopic mature cerebral tissues. Nasal glial heterotopia occurs predominantly in the nasal area and typically does not contain meningothelial elements, whereas heterotopic meningeal nodules occur predominantly on the scalp and do not contain glial elements. In this article, we report an unusual case of cutaneous heterotopia on the nose of an infant composed of both glial and meningothelial elements. The glial component was characterized by irregular islands of predominantly astrocytic cells, on a fibrillary background. The meningothelial component was characterized by bland ovoid cells with focal intranuclear inclusions forming whorled arrangements, with associated psammomatous calcification. To our knowledge, this is the first time such a lesion has been documented. It has also provided us with an opportunity to review the literature regarding heterotopic deposits of both glial and meningothelial tissues. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|