Complete bilateral horizontal gaze paralysis disclosing multiple sclerosis
| Autor: | H Dechy, P Le Hoang, C Pierrot-Deseilligny, Jean Yves Delattre, M Napolitano, D Milea |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2001 |
| Předmět: |
Adult
medicine.medical_specialty Multiple Sclerosis Internuclear ophthalmoplegia Short Report Functional Laterality Ocular Motility Disorders Paralysis Medicine Humans Paresis business.industry Cranial nerves Eye movement Brain Anatomy Medial longitudinal fasciculus medicine.disease Magnetic Resonance Imaging eye diseases Surgery Psychiatry and Mental health Female Neurology (clinical) Brainstem medicine.symptom business |
| Popis: | Two women presented with bilateral internuclear ophthalmoplegia evolving in a few days to complete bilateral horizontal gaze paralysis. Convergence and vertical eye movements were normal. Cerebral MRI showed a few small white matter lesions in the lateral ventricle regions, and, at the brainstem level, a single, small, bilateral lesion affecting the posterior part of the medial pontine tegmentum and responsible for the clinical syndrome. The condition gradually improved in both patients, following a similar progression as at the onset: improvement first involved the adduction movements in both eyes, whereas bilateral abduction paresis still persisted for a few weeks, before complete recovery of eye movements. Bilateral damage to the medial longitudinal fasciculus and subsequent lateral extent of damage to the region of the two abducens emerging fibres may explain the clinical findings. In both cases, the cause was probably multiple sclerosis. |
| Databáze: | OpenAIRE |
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