Arene borylation through C-H activation using Cu3(BTC)2 as heterogeneous catalyst
| Autor: | Hermenegildo García, Amarajothi Dhakshinamoorthy, Cristina Vallés García, Patricia Concepción |
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| Přispěvatelé: | Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España) |
| Rok vydání: | 2021 |
| Předmět: |
Infrared spectroscopy
02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology Heterogeneous catalysis 01 natural sciences Medicinal chemistry Borylation Catalysis 0104 chemical sciences chemistry.chemical_compound chemistry Homogeneous Reagent Metal-organic framework 0210 nano-technology Diborane |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname |
| Popis: | C[sbnd]H borylation by diborane is an important process to access organoboron compounds. Noble metals, including Ir and Rh-based complexes either in the form of homogeneous or heterogeneous catalysts, have been reported to promote arene C[sbnd]H borylation. Recently, metal organic frameworks (MOFs) having Ir and Co as active sites have been used as catalysts, but they require co-catalysts. In the present study, commercially available Cu(BTC) (BTC: 1,3,5-benzenetricarboxylate) MOF is reported as an effective catalyst to promote borylation of arenes through C[sbnd]H activation employing bis(pinacolato)diboron (1) as reagent leading to benzylic and aromatic borylation products. Interestingly, other related MOFs like MIL-101(Cr) and Al(OH)(BDC) (BDC: 1,4-benzenedicarboxylate) do not exhibit catalytic activity under identical conditions. Mechanistic studies using in-situ IR spectroscopy reveal that Cu ions play a crucial role in activating the arene and B[sbnd]B bond in 1. A.D. thanks the University Grants Commission, New Delhi, for the award of an Assistant Professorship under its Faculty Recharge Programme. A.D. also thanks the Department of Science and Technology, India, for the financial support through Extramural Research Funding (EMR/2016/006500). Financial support by the Spanish Ministry of Economy and Competitiveness (Severo Ochoa and RTI2018-089231-CO2-R1) and Generalitat Valenciana (Prometeo 2017-083) is gratefully acknowledged. |
| Databáze: | OpenAIRE |
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